PHARMACEUTICAL DRUGS

Excerpt from "The Lost Language of Plants" by Stephen Harrod Buhner

IN THEIR DRIVE TO CONQUER DISEASE, the supporters of non-technological medicine have created a great many industrial products: pharmaceuticals; personal care products (things such as sunscreens and antibiotic soaps); radiopharmaceuticals and chemotherapy; and pharmaceutical delivery and medical practice products (things such as hypodermic needles, latex gloves, thermometers). All of them end up in the environment. All of them have significant impacts.

PHARMACEUTICAL DRUGS

The vast majority of pharmaceutical drugs do not heal diseases—they control symptoms by introducing chemical mediators, at specific levels, into the body. People with high blood pressure, for example, are not cured when they take medication, which is why they have to take it regularly, often for the rest of their lives. Unlike plants, blood pressure medications, and nearly all pharmaceuticals, are not a normal part of the diet nor a food previously encountered in our evolution. So, the human body excretes them throughout the day in urine and feces: 50-95 percent of each drug taken is excreted chemically unchanged or unmetabolized.1

As blood pressure medication is excreted blood pressure begins to rise and more of the drug must be taken. Drugs used for acute conditions, such as antibiotics, are usually taken short term; those used for chronic conditions such as high blood pressure are usually taken for years or an entire lifetime. In consequence, enormous quantities of pharmaceuticals are going through people's bodies into the environment, where they are proving to have powerfully negative impacts in ecosystems. And the quantity of drugs and other biologically active medical products that are flowing into the environment is increasing every day.

A recent New York Times article observed that "prescription drugs are now the fastest-growing part of the nation's health care bill. That is not so much because manufacturers are raising prices for existing drugs, but because patients are switching to newly approved medicines that cost more, and more prescriptions are being written than ever before."2 Retail prescription sales for pharmaceuticals were $42.7 billion in 1991. In 1999, a mere eight years later, sales were $111.3 billion.3

In the next decade, as the knowledge from the unraveling of the human genome makes even more drugs possible, this figure is expected to increase substantially. At present there are some 500 known chemical receptor sites in the human body affected by drugs. With information from the human genome project this number is expected to soar to between 3,000 and 10,000 sites. As Dr. Gillian Woolett of the Pharmaceutical Research and Manufacturers Association excitedly proclaimed, "The rate of change is absolutely incredible."4

The two scientists who have done the most research on pharmaceuticals in the environment, Christian Daughton (of the U.S. Environmental Protection Agency—EPA) and Thomas Ternes (of the Institute of Water Research and Water Technology in Weisbaden, Germany), comment that "[this] escalating introduction to the marketplace of new pharmaceuticals is adding exponentially to the already large array of chemical classes, each with distinct modes of biochemical action, many of which are poorly understood."5

Many excreted pharmaceuticals and their metabolites are not biodegradable and go on producing chemical effects forever. Most that do biodegrade are regularly replenished by the need for continual dosing or by new prescriptions for new people. As pharmaceuticals are excreted in pure and metabolized forms they also intermix in the waste streams that flow into the environment in ways that cannot be predieted, with effects that are not understood. Researchers have found that metabolites, chemicals produced as by-products of pharmaceutical interaction with the body, tend to be more persistent in the environment, and are sometimes more powerful in their actions, than the drugs from which they are derived.6

In 1999 Americans filled 2.8 billion prescriptions covering roughly sixty-six classes of pharmaceuticals. These include: antidepressants, tranquilizers, and psychiatric drugs; cancer (chemotherapy) drugs; pain killers; anti-inflammatories; antihypertensives; antiseptics; fungicides; anti-epileptics; bronchodilators; lipid regulators (e.g., high-cholesterol medication); muscle relaxants; oral contraceptives; anorectics 1 (diet medication); synthetic hormones; and antibiotics.7

These pharmaceutical drugs and the personal care products also manufactured by many pharmaceutical companies (such as sunscreen lotions, lipsticks, deodorants, perfumes, and shampoos) are produced in staggeringly huge quantities; often equaling or surpassing agro-chemicals in tonnage. The number of pharmaceuticals Americans consume is simply astounding. All of these go into the ecosystem, most of them through excretion into waste treatment systems.

WASTE TREATMENT HERE