PHARMACEUTICALS IN THE ENVIRONMENT
Excerpt from "The Lost Language
of Plants"
by Stephen Harrod Buhner
PHARMACEUTICALS IN THE ENVIRONMENT
In 1992 German researchers, looking for herbicidal
pollution in ground water, were surprised to find high
levels of clofibric acid—a drug used to lower
cholesterol levels in the blood. Subsequent studies
indicated that the North Sea contained roughly 150,000
pounds of clofibric acid. The Danube River and the Po
River (in Italy) were found to contain the same
proportional quantities and the tap water in Berlin
regularly tests between 10 and 165 parts per trillion.
Many Swiss lakes and streams were also found to contain
the drug. Because atmospheric transfer was
systematically ruled out and Switzerland does not
manufacture the drug, the environmental presence of
clofibric acid is now known to come solely from
prescription drug intake and excretion.'5
As concern for pharmaceuticals in the environment
increased many researchers found their work impeded by
the large numbers of pharmaceuticals they were finding
and the cost of identifying them. Each researcher must
obtain an exceptionally expensive "library" of the
chemical profiles of all pharmaceutical drugs so that
when they find an unidentified chemical profile through
gas chromatography they can match it to one in the
library. To date, German scientists have found anywhere
from thirty to sixty pharmaceuticals in water samples
they have examined in numerous countries—tap, surface,
and ground water.16
Most pharmaceuticals are designed to resist breakdown,
to persist, so that they can carry out their metabolic
regulatory activities without interference from the
body. In consequence many are extremely long lived.
Researchers have tracked one plume of contaminated
ground water from a landfill at Jackson Naval Air
Station in Florida that has been slowly moving
underground for more than twenty years. It still
contains such drugs as pentobarbital, meprobamate, and
phensuxim-ide—a barbiturate, a tranquilizer, and an
anticonvulsant.17
Approximately one-third of pharmaceuticals are also
designed to be only lipophilic—not water soluble—so that
they only dissolve in fat. Lipophilic substances can
readily pass through cell walls and chemically act
inside them. In the environment these substances tend to
concentrate in the food chain in the stored fat of all
creatures. In consequence, carnivores higher up the food
chain ingest increasingly large amounts of concentrated
pharmaceuticals.
The top ten prescription medications in the United
States (by number of prescriptions dispensed) are:
Premarin (a conjugated estrogen hormone made from
pregnant mares' urine), Synthroid (a synthetic thyroid
hormone), Lipitor (a cholesterol-lowering drug),
Prilosec (a protein pump inhibitor that stops acid
secretion in treating ulcers), Hydrocodone w/APAP (a
narcotic pain reliever), Albuterol (a bronchial
dilator), Norvasc (for high blood pressure), Claritin
(an antihistamine), Trimox (an antibiotic), and Prozac
(a mood regulator).'8 Eight of these are drugs that are
used for months to years at a time. And they are being
prescribed in ever increasing numbers.
The sales of Lipitor rose 46 percent from 1998 to 1999
while sales of all statins (cholesterol-lowering drugs
such as Lipitor) rose 20 percent. Lipitor costs $3 per
pill and is taken once per day; Pfizer reported sales of
the drug in 1999 at 3.56 billion dollars. Approximately
5 million Americans take statins daily and physicians
and pharmaceutical companies want to raise that number,
perhaps to as high as 20 million—an increase of 400
percent—to treat what they feel are the many undiagnosed
people who need it. Although physicians such as Dr.
Antonio Gotto, dean of Cornell University Medical
College, call statins "very safe drugs"19 for treating
high cholesterol, he, like other researchers, is only
looking at short-term effects in humans without any
reference to their environmental impact.
Normally demonized by the press, cholesterol is actually
an important natural substance, essential for all
cellular functions in all animals. Statins such as
Lipitor inhibit an enzyme—HMG CoA reductase— that is
needed for cholesterol production to take place in
living organisms. Like clofibric acid, the
cholesterol-lowering drug found by Germans in water in
Europe, Lipitor and other statins—taken daily for many
years by millions of people—are flowing into the
environment in huge quantities, where they will continue
to inhibit HMG CoA reductase in whatever organisms
ingest it.
REDUCED SPERM
COUNT - THE TRUE CULPRIT
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